Recognition structures on natural killer cells
نویسندگان
چکیده
منابع مشابه
Increased Natural Killer Cells Activity in Schizophrenic Patients
Background: Schizophrenia has been associated with altered immunity. Different studies regarding natural killer cell activity (NKA) in schizophrenic patients have shown inconsistent results. Objectives: To evaluate NK cell activity in schizophrenic patients in comparison with healthy control individuals. Methods: 30 medication-free schizophrenic patients and 41 healthy sex, age and smoking st...
متن کاملRecognition of vaccinia virus-infected cells by human natural killer cells depends on natural cytotoxicity receptors.
Natural Killer (NK) cells are important in the immune response to a number of viruses; however, the mechanisms used by NK cells to discriminate between healthy and virus-infected cells are only beginning to be understood. Infection with vaccinia virus provokes a marked increase in the susceptibility of target cells to lysis by NK cells, and we show that recognition of the changes in the target ...
متن کاملRecognition of infected cells by natural killer cells.
Under the influence of cytokines associated with innate immunity, natural killer (NK) cells rapidly become activated and migrate to sites of infection. Upon contact with infected parenchyma they proliferate, release cytokines and/or kill cells harboring pathogens. Multiple stimulatory and inhibitory receptors can provide the integrated signals that trigger this contact-mediated NK-cell function...
متن کاملTurning on Natural Killer Cells
NK cells preferentially recognize and kill cells that lack expression of MHC class I (1). While inhibitory receptors expressing immunoreceptor tyrosine-based inhibition motifs prevent NK cells from harming tissues expressing normal levels of classical or nonclassical MHC class I (for a review , see reference 2), what turns on NK cells? Recent reports (3, 4), including Smith et al. in this issue...
متن کاملRecognition of Microbial Glycolipids by Natural Killer T Cells
T cells can recognize microbial antigens when presented by dedicated antigen-presenting molecules. While peptides are presented by classical members of the major histocompatibility complex (MHC) family (MHC I and II), lipids, glycolipids, and lipopeptides can be presented by the non-classical MHC member, CD1. The best studied subset of lipid-reactive T cells are type I natural killer T (iNKT) c...
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ژورنال
عنوان ژورنال: Japanese Journal of Clinical Immunology
سال: 1994
ISSN: 0911-4300,1349-7413
DOI: 10.2177/jsci.17.752